How do you read a file into a list in Python?

I want to prompt a user for a number of random numbers to be generated and saved to a file. He gave us that part. The part we have to do is to open that file, convert the numbers into a list, then find the mean, standard deviation, etc. without using the easy built-in Python tools.

I've tried using open but it gives me invalid syntax (the file name I chose was "numbers" and it saved into "My Documents" automatically, so I tried open(numbers, 'r') and open(C:\name\MyDocuments\numbers, 'r') and neither one worked).